Theanine pill side effects dosage research for anxiety

L-Theanine is one of the major amino acid components in green tea, and black tea. There’s been very little research regarding theanine supplementation in humans, therefore we don’t have a clear idea of benefits or risks. Theanine (r-glutamylethylamide) studies suggest that this amino acid affects neurotransmission, especially inhibitory neurotransmission.

Theanine side effects
These include sedation, but mostly this product is relatively safe. Yohimbe bark can cause anxiety and difficulty with sleep.

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L-Theanine is an amino acid that helps promote a mild, restful, relaxed state without diminishing daytime alertness. It’s free of the side effects commonly associated with other relaxing agents.

Suntheanine, a patented form of L Theanine, is a trademark of Taiyo International, Inc.
Promotes relaxation and stress reduction

Supplement Facts
L Theanine 100 mg dosage
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Theanine clinical benefit
Orally administered theanine is absorbed through the intestinal tract and hydrolyzed in the liver to glutamic acid and ethylamine. Ethylamine, a molecule that primes the response of an immune system element called the gamma-delta T cell, which may protect against infection.
Theanine might be useful for preventing ischemic neuronal damage.
Increases the idarubicin-induced antitumor activity and ameliorates its toxicities.
Could be helpful for sleep and reducing anxiety. Another supplement for anxiety help is 5HTP.
Human research with theanine is limited, and hence the clinical usefulness of theanine is not clear at this time.

Theanine and brain health
Theanine prevents memory impairment induced by repeated cerebral ischemia in rats.
Phytother Res. 2007; Department of Pharmacy, Kyushu University Hospital, Fukuoka 812-8582, Japan.
The present study investigated the neuroprotective effect of theanine on memory impairment induced cerebral ischemia in rats. Theanine was injected i.p.. Theanine significantly prevented the impairment of spatial memory in rats subjected to repeated cerebral ischemia, These results suggest that theanine prevents memory impairment induced by repeated cerebral ischemia, in part by protecting against neuronal cell death, and that it might be useful for preventing cerebrovascular disease.

Theanine Research for obesity
Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice.
Zheng G. hizuoka University, Ohya, Shizuoka-shi, Japan.
In Vivo. 2004.
To elucidate the anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, female ICR mice were fed on diets containing 2% green tea powder and diets containing 0.3% catechins, 0.05% caffeine and 0.03% theanine, which correspond, respectively, to their concentrations in a 2% green tea powder diet, singly and in combination for 16 weeks. Body weight and food intake were determined monthly during this period, kidneys, adrenals, liver, spleen, brain, pituitary and intraperitoneal adipose tissues (IPAT) were weighed and lipid levels in the serum and liver were measured at the end of this period. The body weight increase and weight of IPAT were significantly reduced by the diets containing green tea, caffeine, theanine, caffeine + catechins, caffeine + theanine and caffeine + catechins + theanine. Noticeably, the IPAT weight decreased by 76% in the caffeine + catechins compared to the control group. Serum concentrations of triglycerides (TG) and non-esterified fatty acids (NEFA) were decreased by green tea, catechins and theanine. Moreover, caffeine + catechins, caffeine + theanine and caffeine + catechins + theanine also decreased NEFA in the serum. The TG level in the liver was significantly reduced by catechins and catechins + theanine in comparison with the control. These results indicated that at least caffeine and theanine were responsible for the suppressive effect of green tea powder (GTP) on body weight increase and fat accumulation. Moreover, it was shown that catechins and caffeine were synergistic in anti-obesity activities.